Ribosomal protein L11, RNA binding domain
|Literature||1. Markus MA, Hinck AP, Huang S, Draper DE, Torchia DA; Nat Struct Biol 1997;4:70-77.High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA. PUBMED:8989327|
2. Hinck AP, Markus MA, Huang S, Grzesiek S, Kustonovich I, Draper DE; J Mol Biol 1997;274:101-113.The RNA binding domain of ribosomal protein L11: Three- dimensional structure of the RNA-bound form of the protein and its interaction with 23S rRNA. PUBMED:9398519
The seed alignment for this family in the PANDIT database contains 13 aligned sequences:
| || RK11_SPIOL/142-210 RL11_BACSU/70-138 RL11_ECOLI/71-139 RL11_HALN1/66-134 RL11_LIBAS/71-139 RL11_STRGR/74-142 RL11_SULAC/68-136 RL11_SYNY3/71-139 RL11_THEMA/70-138 RL11_THETH/70-138 RL12_HUMAN/75-143 RL12_YEAST/75-143 RM11_CAEEL/86-155 |
The full alignment for this family in the Pfam database contains 1967 aligned sequences
Species in the seed alignment
List of species covered in the seed alignment. The number in brackets denotes the number of sequences taken from each organism.
| ||Caenorhabditis elegans (1); Homo sapiens (1); Thermotoga maritima (1); Sulfolobus acidocaldarius (1); Candidatus Liberibacter asiaticus (1); Escherichia coli K12 (1); Spinacia oleracea (1); Saccharomyces cerevisiae (1); Thermus thermophilus (1); Synechocystis sp. PCC 6803 (1); Streptomyces griseus (1); Halobacterium salinarum (1); Bacillus subtilis (1);|
The full alignment covers 1013 species.
Pre-computed estimates from Markov codon substitution models (explanation)
Following are maximum-likelihood estimates and log-likelihood scores from codon models M0, M1, M2, M7 and M8, implemented in PAML v.4.1
Maximum-likelihood estimates and log-likelihood scores from codon models Nonsynonymous and Dual implemented in HYPHY
|Interactions||This domain has 2 known interactions:|
|Structures||This domain has 120 structures:|
|Notation: PDB_ID (PDB chain, PDB residues)|
|KEGG Pathways - for genes coding for sequences from full alignment|
|DisProt- disorder annotation inferred from homologous DisProt sequences|
|ρD/ρO = 1.3099 (p-value = 3.1608e-13)|
Expression data (explanation)
|Bgee expression data - for genes coding for sequences from seed alignment Click here for overview of Bgee data|
The numbers in brackets correspond to the number of genes that are associated with the selected family and are expressed in the corresponding tissue. Click on the tissue to see all the families that possibly have function in that tissue and click on the genes to see the corresponding genes.
|HumanProteinpedia expression data - for human genes coding for sequences from full alignment Click here for overview of Human Proteinpedia data|
The numbers in brackets correspond to the number of human genes that are associated with the selected family and are expressed in the corresponding tissue. Click on the tissue to see all the families that possibly have function in that tissue and click on the genes to see the corresponding genes.
Human disease association
|Genetic Association Database - data for human genes coding for sequences from full alignment|
|Associated diseases and disorders|
|Links to OMIM - for human genes coding for sequences from full alignment|
|180475 (1) 611826 (1)|